Bévitine 100 mg / 2 ml Vitamin B1 Injectable Solution in Ampoules

Why use BEVITINE 100 mg/2 mL solution for injection?

Vitamin B1 (thiamine) plays an essential role in carbohydrate metabolism and the normal functioning of the nervous and muscular systems. In certain cases of severe malnutrition, digestive malabsorption, chronic alcoholism, or acute gastrointestinal disorders, oral intake is no longer sufficient.

BEVITINE 100 mg/2 mL provides a direct parenteral solution:

1. Rapid correction of acute thiamine deficiencies: Each ampoule provides 100 mg of anhydrous thiamine hydrochloride, which the body can absorb directly without passing through the digestive tract.
2. Support for the nervous system and energy metabolism: Prevents and treats neurological and cardiac complications associated with vitamin B1 deficiency (neuritis, encephalopathies, Wernicke-Korsakoff syndrome).
3. Safe parenteral administration: Can be administered intramuscularly (IM) or by slow intravenous (IV) injection when oral administration is not feasible.

Indications and Benefits of Treatment

This injectable vitamin B1 medication is recommended for adults for:

• The curative treatment of medically confirmed vitamin B1 deficiencies.
• Administration in patients with digestive disorders that prevent the absorption of thiamine when taken orally.

Directions for Use and Dosage: Bévitine 100 mg/2 mL Solution for Injection in Ampoules

This medication is intended for adults only. Administration must be performed by a healthcare professional or strictly in accordance with a physician’s prescription.

Usual dosage: 1 to 2 ampoules per day.

Higher doses: In severe cases, your doctor may prescribe higher doses. For doses exceeding 2 ampoules per day, the total dose must be spread out over a 24-hour period.

Route of administration:

• Intramuscular (IM).
• By slow intravenous (IV) injection (the injection must be administered over at least 10 minutes).

Composition and Active Ingredients

For a 2-mL ampoule:

• Active ingredient: Thiamine hydrochloride (104.00 mg), equivalent to 100.00 mg of anhydrous thiamine hydrochloride.
• Excipients: Thiomalic acid, sodium hydroxide, sodium hydrogen phosphate dodecahydrate, water for injection.

Precautions and Contraindications

• Contraindications: Never use in patients with a history of allergy or hypersensitivity to thiamine hydrochloride or to any of the excipients.
• Special Precautions: Risk of severe allergic reactions (anaphylactic shock) during intravenous injection; therefore, administration must be very slow (over 10 minutes).
• Pregnancy and breastfeeding: It is best not to use this medication during pregnancy. If breastfeeding, use of this treatment should be avoided. Always consult a doctor before administration.

In what cases is BEVITINE injection used instead of tablets?

BEVITINE in ampoules is prescribed when the patient cannot swallow tablets (swallowing difficulties, vomiting), in cases of severe intestinal malabsorption, or when an extremely rapid replenishment of vitamin B1 is medically necessary.

How is a 100 mg/2 mL ampoule of BEVITINE administered?

The injection may be administered intramuscularly or by slow intravenous infusion (over a period of more than 10 minutes) by a qualified healthcare professional.

Does this medication require any special precautions during injection?

Yes, intravenous injections of vitamin B1 must be administered very slowly to avoid potential severe allergic reactions or drops in blood pressure.