Advil Caps 400 mg 14 capsules

Description:

It is indicated in adults, after at least one medical opinion, in the treatment of mild to moderate migraine attacks, with or without aura.

Route of administration

oral

Dosage

Dosage

Painful and/or febrile conditions

Suitable for adults and children weighing over 30 kg (11-12 years).

The usual dosage is 1 capsule of 400 mg per dose, to be repeated if necessary every 6 to 8 hours, without exceeding 3 capsules of 400 mg per day (1200 mg per day).

The 400 mg capsule is reserved for pain or fever that is more intense or not relieved by a 200 mg ibuprofen capsule.

As the elderly are at increased risk of adverse effects, use the lowest possible dose for the shortest time necessary to relieve symptoms.

Do not exceed recommended doses or duration of treatment (3 days for fever, 5 days for pain).

The maximum dosage is 3 capsules per day (1200 mg).

In case of migraine attack

RESERVED FOR ADULTS

1 capsule at 400 mg as soon as possible after the onset of the attack.

If a patient is not relieved after the first dose, a second dose should not be taken during the same attack. However, the attack may be treated with another non-steroidal anti-inflammatory drug or aspirin.

If the pain recurs, a second dose may be taken provided that an interval of 8 hours is observed between the 2 doses.

If in doubt, ask your doctor or pharmacist for advice.

How to take it

Take by mouth.

Swallow the capsule, without chewing, with a large glass of water.

The capsules should preferably be taken with a meal.

Frequency of administration

Systematic administration avoids fluctuations in pain or fever.

They should be taken at least 6 hours apart.

Duration of treatment

The duration of use is limited to:

• 3 days in case of fever,
• 3 days in case of migraine,
• 5 days in case of pain

If the pain persists for more than 5 days or the fever for more than 3 days, if they worsen or if a new disorder occurs, inform your doctor.

In case of a migraine attack, the duration of treatment should not exceed 3 days.

If the symptoms persist and worsen or if new symptoms appear, ask your pharmacist or doctor for advice.

If you feel that the effect of ADVILCAPS 400 mg, softgel is too strong or too weak: consult your doctor or pharmacist.

Composition

Ibuprofen

Contraindications

Do not take ADVILCAPS 400 mg, soft capsule in the following cases:

- after 5 months of pregnancy (24 weeks of amenorrhea),

- a history of allergy or asthma triggered by this or related drugs, including other non-steroidal anti-inflammatory drugs, acetylsalicylic acid (aspirin),

- a history of allergy to other components of the softgel,

- history of gastrointestinal bleeding or ulcers from previous NSAID therapy,

- active or recurrent ulcer or bleeding from the stomach or intestine,

- ongoing gastrointestinal hemorrhage, brain hemorrhage or other bleeding,

- severe liver disease,

- severe kidney disease,

- severe heart disease,

- systemic lupus erythematosus.

IN CASE OF DOUBT, IT IS ESSENTIAL TO ASK YOUR DOCTOR OR PHARMACIST FOR ADVICE.

Precautions for use

Take special precautions with ADVILCAPS 400 mg, soft capsule:

At high doses, above 1200 mg/day, this drug has anti-inflammatory properties and may cause sometimes serious drawbacks which are those observed with non-steroidal anti-inflammatory drugs.

Drugs such as ADVILCAPS 400 mg, softgel may increase the risk of heart attack ("myocardial infarction") or stroke. The higher the dose and the longer the duration of treatment, the greater the risk.

Do not exceed the recommended doses or duration of treatment.

If you have heart problems, have had a stroke, or think you may have risk factors for heart disease (for example, high blood pressure, diabetes, high cholesterol, or smoking), please talk to your doctor or pharmacist.

Special Warnings

If you are a woman, ADVILCAPS 400 mg, softgel may affect your fertility. It is not recommended for use in women who wish to conceive a child. In women who have difficulty conceiving or in whom reproductive tests are being performed, please talk to your doctor or pharmacist before taking ADVILCAPS 400 mg, Softgels.

Elderly subjects have a higher risk of adverse reactions, especially gastrointestinal bleeding, ulcers and perforations. Renal, hepatic and cardiac function should be closely monitored. The dosage should be kept as low as possible for the shortest period of time necessary to relieve symptoms.

The use of this drug is not recommended in patients with fructose intolerance (a rare hereditary disease).

BEFORE USING THIS MEDICATION, CONSULT YOUR DOCTOR IN CASE OF:

- a history of asthma associated with chronic rhinitis, chronic sinusitis or polyps in the nose. Administration of this medicine may cause an asthma attack, especially in certain people who are allergic to acetylsalicylic acid (aspirin) or to a non-steroidal anti-inflammatory drug (see section "Never take ADVILCAPS 400 mg, softgel in the following cases"),

- coagulation disorders, taking an anticoagulant treatment. This medicine may cause serious gastrointestinal manifestations,

- a history of digestive problems (hiatal hernia, digestive haemorrhage, ulcer of the stomach or duodenum),

- heart, liver or kidney disease,

- chicken pox. This medication is not recommended due to exceptional severe skin infections,

- Concomitant treatment with other drugs that increase the risk of peptic ulcer or bleeding, for example, oral corticosteroids, antidepressants (those of the SSRI type, i.e. Selective Serotonin Reuptake Inhibitors), drugs that prevent blood clots such as aspirin, or anticoagulants such as warfarin If you have any of these conditions, talk to your doctor before taking ADVILCAPS 400 mg, softgel (see "Taking or using other medicines"),

- if you are taking methotrexate at doses higher than 20 mg per week or pemetrexed (see "Taking or using other medicines").

DURING TREATMENT, IN CASE OF:

- visual disturbances, Warn your doctor,

- Gastrointestinal haemorrhage (discharge of blood from the mouth or stools, black stools), STOP THE TREATMENT AND CONTACT A PHYSICIAN OR EMERGENCY MEDICAL SERVICE IMMEDIATELY,

- signs on the skin or mucous membranes that resemble a burn (redness with bullae or blisters, ulcerations), STOP THE TREATMENT AND CONTACT A PHYSICIAN OR EMERGENCY MEDICAL SERVICE IMMEDIATELY,

- signs of allergy to this medicine, including asthma attack or sudden swelling of the face and neck (see "What are the possible side effects?"), STOP THE TREATMENT AND CONTACT A PHYSICIAN OR EMERGENCY MEDICAL SERVICE IMMEDIATELY.

This medicine contains a non-steroidal anti-inflammatory drug: ibuprofen.

You should not take other medicines containing non-steroidal anti-inflammatory drugs (including selective cyclooxygenase 2 inhibitors) and/or acetylsalicylic acid (aspirin) with this medicine. Carefully read the package inserts of other medications you are taking to make sure they do not contain NSAIDs and/or acetylsalicylic acid (aspirin).

Dosage

400 mg

Presentation

Box of 14